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Methoxetamine first made an appearance as another ‘legal high’. A number of people over forums/chat rooms have compared it to ketamine referring it to a “bladder friendly” ketamine. However this has never been tested and therefore cannot be deemed correct. Others claim that although it may have a similar effect to ketamine, the after effects, or comedown is considerably worse than ketamine. There is very little concrete information available for methoxetamine. Please see ‘research chemicals’ section for more information and advice on the use of new drugs.
MXE can also cause a range of negative side effects, including sensory distortions, paranoia, and problems with speech and communication. Despite legal restrictions placed on the recreational use of similar drugs, PCP and ketamine. There are currently no federal restrictions on the sale of MXE in the United States
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What Does MXE Do?
There are several ways that people take MXE. Some take it orally or sublingually (under the tongue). Some take it by nasal insufflation or snorting it into the nose. It can also be inserted into the rectum, where it’s absorbed into the bloodstream, or injected into a muscle.
Like other psychoactive drugs, the MXE high is described as pleasurable and includes stimulant, relaxant, and dissociative effects. But MXE also has unpredictable and intense side effects—particularly with higher doses—that are extremely unpleasant both physically and psychologically.