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What are the effects ?

The effects of ayahuasca can vary widely. In general, this powerful, unique beverage can give rise to some truly special experiences. A common effect is a spiritual experience accompanied by deep reflection. When taking ayahuasca, it often happens that people take a philosophical approach to their place in the world and the essence of nature. The sensation is refer to as a “rebirth” by many people. Of course, the experience is different for everyone, but the general consensus is that ayahuasca can result in a trip that awakens a variety of spiritual feelings.

Potential effects

Most people have a very special experience during an ayahuasca session. Under the direction of a shaman (or someone with similar knowledge and experience), it is often follow by discussions on spiritual topics and your deepest desires. Some people refer to it as a spiritual awakening or rebirth. Once again, this is not necessarily the case for everyone, but chances are definitely high that you will feel like a different person after a session.

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This is a South American entheogenic brew commonly made out of the Banisteriopsis caapi vine, the Psychotria viridis shrub or a substitute, and possibly other ingredients;although, in the West, a chemically similar preparation also known and sold as ayahuasca, but occasionally also known as “pharmahuasca”, can be prepared using illicitly manufactured N,N-Dimethyltryptamine (DMT) and a pharmaceutical monoamine oxidase inhibitor (MAOI) such as isocarboxazid.The brew is used as a traditional spiritual medicine in ceremonies among the indigenous peoples of the Amazon basin.

B. caapi contains several alkaloids that act as MAOIs, which are required for DMT to be orally active. The other required ingredient is a plant that contains the primary psychoactive, DMT. This is usually the shrub P. viridis,but Diplopterys cabrerana may be used as a substitute. Other plant ingredients often or occasionally used in its production  include Justicia pectoralis, one of the Brugmansia (especially Brugmansia insignis and Brugmansia versicolor, or a hybrid breed) or Datura species, and mapacho (Nicotiana rustica).

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It is used largely as a treasured aid to spiritual practice. People who work with ayahuasca in non-traditional contexts often align themselves with the philosophies and cosmologies associated with ayahuasca shamanism, as practiced among indigenous peoples like the Urarina of the Peruvian Amazon.While non-native users know of the spiritual applications of ayahuasca, a less well-known traditional usage focuses on the medicinal properties of ayahuasca. When used for its medicinal purposes, ayahuasca affects the human consciousness for less than six hours, beginning half an hour after consumption and peaking after two hours. In some cases, individuals experience significant psychological stress during the experience. Ayahuasca also has cardiovascular effects, moderately increasing heart rate and diastolic blood pressure. It is for this reason that extreme caution should be taken with those who may be at risk of heart disease.

The psychedelic effects of ayahuasca include visual and auditory stimulation, the mixing of sensory modalities, and psychological introspection that may lead to great elation, fear, or illumination. It may induce intense vomiting and occasional diarrhea.These purgative properties are known as la purga or “the purge”.

Preparation

Sections of Banisteriopsis caapi vine are macerated and boiled alone or with leaves from any of a number of other plants, including Psychotria viridis (chacruna), Diplopterys cabrerana (also known as chaliponga and chacropanga),and Mimosa tenuiflora, among other ingredients which can vary greatly from one shaman to the next. The resulting brew may contain the powerful psychedelic drug DMT and MAO inhibiting harmala alkaloids, which are necessary to make the DMT orally active. The traditional making of ayahuasca follows a ritual process that requires the user to pick the lower Chacruna leaf at sunrise, then say a prayer. The vine must be “cleaned meticulously with wooden spoons” and pounded “with wooden mallets until it’s fibre.”

Brews can also be made with plants that do not contain DMTPsychotria viridis being replaced by plants such as Justicia pectoralisBrugmansia, or sacred tobacco, also known as mapacho (Nicotiana rustica), or sometimes left out with no replacement. This brew varies radically from one batch to the next, both in potency and psychoactive effect, based mainly on the skill of the shaman or brewer, as well as other admixtures sometimes added and the intent of the ceremony. Natural variations in plant alkaloid content and profiles also affect the final concentration of alkaloids in the brew, and the physical act of cooking may also serve to modify the alkaloid profile of harmala alkaloids.

The actual preparation of the brew takes several hours, often taking place over the course of more than one day. After adding the plant material, each separately at this stage, to a large pot of water it is boiled until the water is reduced by half in volume. The individual brews are then added together and brewed until reduced significantly. This combined brew is what is taken by participants in ayahuasca ceremonies.

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