Hallucinogenic mushrooms’ is the name commonly given to psychoactive fungi, containing hallucinogenic compounds, most commonly psilocybin and psilocin. At low doses, hallucinogenic drugs have as their primary effects perceptual distortions and alterations of thought, or mood, with the presence of lucid awareness and minimal effects on memory and orientation. Despite their name, the use of hallucinogenic drugs rarely results in true hallucinations. The hallucinogens are a chemically diverse class. Grouping the hallucinogens based on their chemical structure includes, but is not limited to, three major classes: indolealkylamines or tryptamines (e.g. LSD, psilocybin and psilocin), phenethylamines, including mescaline and methylenedioxymethamphetamine (MDMA); and cannabinoids.
Mode of use
Recreational doses range from 1–5 grams of dry mushrooms depending on the species and individual strength of the specimens. Dosages for fresh mushrooms will be approximately 10 times higher (10–50 grams). The material may be eaten raw, boiled in water to make tea, or cooked with other foods to cover its bitter flavor. After ingestion, the psilocybin is enzymatically converted to psilocin. Absorbed from the gastro-intestinal tract, hallucinogenic effects usually occur within 30 minutes of ingestion with a duration of effect of 4–6 hours.
In the 1960s, pure synthetic psilocybin (Indocybin) was marketed by Sandoz for experimental and psychotherapeutic purposes. At present, there are no medical indications for psilocin or psilocybin. Recent research with psilocybin has been reported on the treatment of compulsive disorders in humans.
In the past few years, a growing number of studies using human volunteers have begun to explore the possible therapeutic benefits of drugs such as psilocybin, LSD, DMT, MDMA, ibogaine and ketamine. These studies are looking at psilocybin and other hallucinogens to treat a number of otherwise intractable psychiatric disorders, including chronic depression, post-traumatic stress disorder, and drug or alcohol dependency.
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